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Article

Identification of Mutations Associated With Macozinone-Resistant in Mycobacterium Tuberculosis.

Current microbiology - 26 May 2022

Chen Xi, Li Yuanyuan, Wang Bin, Lu Yu

Abstract excerpt

Novel anti-tuberculosis drug macozinone (MCZ) is identified as a drug candidate and is currently under clinical development for the treatment of tuberculosis. However, the mutations conferring resistance to MCZ remain inadequately characterized. In this study we investigated resistant mutations to the MCZ through de novo resistance selection in vitro. This was accomplished by passing the Mycobacterium...

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PMID: 35616769
DOI: 10.1007/s00284-022-02881-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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