Article
PD-L1 expression and FGFR-mutations among Danish patients diagnosed with metastatic urothelial carcinoma: A retrospective and descriptive study.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Aug 2022
Grantzau Trine, Toft Birgitte Grønkaer, Melchior Linea Cecilie, Elversang Johanna, Stormoen Dag Rune, Omland Lise Høj, Pappot Helle
Abstract excerpt
Checkpoint inhibitors have changed the treatment landscape of advanced urothelial carcinoma (mUC), and recently, a fibroblast-growth-factor-receptor (FGFR) inhibitor has been introduced. This study aimed at estimating programmed death-ligand 1 (PD-L1) expression in primary tumors (PTs) and the PD-L1 expression concordance between PTs and paired metastases in 100 patients with UC managed in the real-world setting....
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