Article
Prognostic Effect of FGFR Mutations or Gene Fusions in Patients with Metastatic Urothelial Carcinoma Receiving First-line Platinum-based Chemotherapy: Results from a Large, Single-institution Cohort.
European urology focus - 1 Sept 2019
Necchi Andrea, Lo Vullo Salvatore, Raggi Daniele, Gloghini Annunziata, Giannatempo Patrizia, Colecchia Maurizio, Mariani Luigi
Abstract excerpt
FGFR gene alterations represent a target for treatment in clinical trials of urothelial carcinoma (UC). Little is known about their prognostic effect in patients with metastatic UC. We analyzed data for 112 patients treated with platinum-based first-line chemotherapy at our center between October 2011 and March 2017 and who were screened for the presence of FGFR mutations or gene fusions within multiple clinical...
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