Article
Correlation between fibroblast growth factor receptor mutation, programmed death ligand-1 expression and survival in urinary bladder cancer based on real-world data.
Pathology oncology research : POR - 1 Jan 2023
Revesz Janos, Posfai Boglarka, Pajor Laszlo, Papdan Timea, Varga Linda, Paczona Viktor R, Varga Zoltan, Sukosd Farkas, Maraz Aniko
Abstract excerpt
Background: Programmed cell death (PD)-1/PD-ligand 1 (PD-L1) inhibitors have made a breakthrough in the therapy of advanced urothelial bladder cancer (UBC). The impact of Fibroblast Growth Factor Receptor 3 (FGFR3) mutation on the effectiveness of PD-L1 treatment remains still unclear. Objective: Our study aimed to investigate the frequency of FGFR mutations at different tumor stages, and their relation to PD-L1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.