Article
Chronic Myelomonocytic Leukemia: a Genetic and Clinical Update.
Current hematologic malignancy reports - 1 Sept 2015
McCullough Kristen B, Patnaik Mrinal M
Abstract excerpt
Chronic myelomonocytic leukemia (CMML) is a clonal stem cell disorder, characterized by peripheral blood monocytosis and overlapping features between myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs). Clonal cytogenetic changes are seen in up to 30 % patients, while approximately 90 % have detectable molecular abnormalities. Most patients are diagnosed in the seventh decade of life. Gene...
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