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Article

BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation.

BMC bioinformatics - 24 May 2022

Yu Wen-Yi, Zhang Yu, Li Meng-Kai, Yang Zi-Ying, Fung Wing Kam, Zhao Pei-Zhen, Zhou Ji-Yuan

Abstract excerpt

BACKGROUND: X chromosome inactivation (XCI) is an epigenetic phenomenon that one of two X chromosomes in females is transcriptionally silenced during early embryonic development. Skewed XCI has been reported to be associated with some X-linked diseases. There have been several methods measuring the degree of the skewness of XCI. However, these methods may still have several limitations. RESULTS: We propose a...

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Identifiers

PMID: 35610583
DOI: 10.1186/s12859-022-04721-y
PMCID: PMC9128296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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