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Article

Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration.

Translational vision science & technology - 2 May 2022

Marin A Itzam, Poppelaars Felix, Wagner Brandie D, Palestine Alan G, Patnaik Jennifer L, Holers V Michael, Frazer-Abel Ashley A, Mathias Marc T, Manoharan Niranjan, Fonteh Cheryl N, Mandava Naresh, Lynch Anne M

Abstract excerpt

Purpose: Age-related macular degeneration (AMD) is an acquired degenerative disease of the retina classified into early, intermediate, and advanced AMD. A key factor in the pathogenesis of AMD is the complement system. The interaction of age and sex with the complement system may affect the risk of developing AMD. The purpose of this study was to determine if there were sex-specific differences in levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35594041
DOI: 10.1167/tvst.11.5.22
PMCID: PMC9145081

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