Article
Shared genetic architectures of subjective well-being in East Asian and European ancestry populations.
Nature human behaviour - 1 Jul 2022
Kim Soyeon, Kim Kiwon, Hwang Mi Yeong, Ko Hyunwoong, Jung Sang-Hyuk, Shim Injeong, Cha Soojin, Lee Hyewon, Kim Beomsu, Yoon Joohyun, Ha Tae Hyon, Kim Doh Kwan, Kim Jinho, Park Woong-Yang, Okbay Aysu, Kim Bong-Jo, Kim Young Jin, Myung Woojae, Won Hong-Hee
Abstract excerpt
Subjective well-being (SWB) has been explored in European ancestral populations; however, whether the SWB genetic architecture is shared across populations remains unclear. We conducted a cross-population genome-wide association study for SWB using samples from Korean (n = 110,919) and European (n = 563,176) ancestries. Five ancestry-specific loci and twelve cross-ancestry significant genomic loci were...
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