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Entanglement of Methylation Changes and cGAS-STING Signaling in Non-Small-Cell Lung Cancer

19 May 2022

Abstract excerpt

BACKGROUND: cGAS-STING signaling has been primarily discovered as an important DNA sensing machinery, bridging innate immunity and adaptive immunity. Beyond its antiviral response, recent evidence expanded its complicated role in cancer therapy. METHODS: UALCAN, The TCGA Wander, GEPIA, SMART, TIMER, Kaplan-Meier plotter, TCGA Data, and cBioPortal were utilized in the investigation. RESULTS: We evaluated the...

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PMID: 35585823
DOI: 10.2174/1386207325666220517095503

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