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Article

New Insights Relating Gasdermin B to the Onset of Childhood Asthma.

American journal of respiratory cell and molecular biology - 1 Oct 2022

Schoettler Nathan, Dissanayake Eishika, Craven Mark W, Yee Jeremiah S, Eliason Joshua, Schauberger Eric M, Lemanske Robert F, Ober Carole, Gern James E

Abstract excerpt

Chromosome 17q12-q21 is the most replicated genetic locus for childhood-onset asthma. Polymorphisms in this locus containing ∼10 genes interact with a variety of environmental exposures in the home and outdoors to modify asthma risk. However, the functional basis for these associations and their linkages to the environment have remained enigmatic. Within this extended region, regulation of GSDMB (gasdermin B)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35580164
DOI: 10.1165/rcmb.2022-0043PS
PMCID: PMC9564923

Genes

GSDMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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