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Article

Interplay between stress response genes associated with attention-deficit hyperactivity disorder and brain volume.

Genes, brain, and behavior - 1 Sept 2016

van der Meer D, Hoekstra P J, Bralten J, van Donkelaar M, Heslenfeld D J, Oosterlaan J, Faraone S V, Franke B, Buitelaar J K, Hartman C A

Abstract excerpt

The glucocorticoid receptor plays a pivotal role in the brain's response to stress; a haplotype of functional polymorphisms in the NR3C1 gene encoding this receptor has been associated with attention-deficit hyperactivity disorder (ADHD). The serotonin transporter (5-HTT) gene polymorphism 5-HTTLPR is known to influence the relation between stress exposure and ADHD severity, which may be partly because of its...

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Share to Attention Deficit Disorder with Hyperactivity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27391809
DOI: 10.1111/gbb.12307

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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