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Can We Treat Neurodegenerative Proteinopathies by Enhancing Protein Degradation?

17 May 2022

Abstract excerpt

Neurodegenerative proteinopathies are defined as a class of neurodegenerative disorders, with either genetic or sporadic age-related onset, characterized by the pathological accumulation of aggregated protein deposits. These mainly include Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD) as well as frontotemporal lobar degeneration (FTLD). The...

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PMID: 35579450
DOI: 10.1002/mds.29058

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