VNTR Polymorphism in Intron 4 of the eNOS Gene and the Risk of Gastrointestinal Bleeding: A Case-control Study.

doi:10.15403/jgld-4226

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Article

VNTR Polymorphism in Intron 4 of the eNOS Gene and the Risk of Gastrointestinal Bleeding: A Case-control Study.

Journal of gastrointestinal and liver diseases : JGLD - 12 Jun 2022

Forgerini Marcela, Urbano Gustavo, De Nadai Tales Rubens, Zanelli Cleslei Fernando, Valentini Sandro Roberto, Mastroianni Patrícia De Carvalho

Abstract excerpt

BACKGROUND AND AIMS: Considering the lack of knowledge regarding the influence of the variable number of repeats of 27 pb in intron 4 (4b/4a VNTR - rs61722009) of the endothelial nitric oxide synthase (eNOS) on the drug response, we assessed the influence of this polymorphism for the risk of upper gastrointestinal bleeding (UGIB). METHODS: A case-control study, including 200 cases and 706 controls, was conducted...

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PMID: 35574622
DOI: 10.15403/jgld-4226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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