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Article

Influence of IL-β, IL-1RN, and TNF-α variants on the risk of acetylsalicylic acid-induced upper gastrointestinal bleeding: a case-control study.

Einstein (Sao Paulo, Brazil) - 1 Jan 2024

Forgerini Marcela, Zanelli Cleslei Fernando, Valentini Sandro Roberto, Mastroianni Patrícia de Carvalho

Abstract excerpt

OBJECTIVE: Forgerini et al. investigated the role of seven genetic variants in the risk of upper gastrointestinal bleeding as an adverse drug reaction. In 289 participants (50 cases and 189 controls), the presence of seven variants in the IL-1β, IL-1RN, and TNF-α genes was not associated with susceptibility to acetylsalicylic acid-induced upper gastrointestinal bleeding. The use of acetylsalicylic acid, even in...

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Identifiers

PMID: 39194098
DOI: 10.31744/einstein_journal/2024AO0746
PMCID: PMC11319029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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