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Article

Bleeding duodenal ulcer and association with polymorphism of endothelial constitutive nitric oxide synthase gene.

Digestive diseases and sciences - 1 May 2002

Serrano Trinidad, Piazuelo Elena, Benito Rafael, Santolaria Santos, Lanas Angel

Abstract excerpt

Nitric oxide (NO) exerts both protective and proinflammatory actions in the gastrointestinal tract. Enhanced gastric NO synthase (NOS) activity has been shown in duodenal ulcer patients. Recently, intron-4 polymorphism of the endothelial constitutive (ec) NOS gene has been associated with some pathological conditions. Our aim was to determine the genotype and allele frequencies of the ecNOS4 polymorphism in...

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PMID: 12018926
DOI: 10.1023/a:1015021603681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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