The role of CYP2C9*2, CYP2C9*3 and VKORC1-1639 variants on the susceptibility of upper gastrointestinal bleeding: A full case-control study.

doi:10.3389/jpps.2023.11136

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Article

The role of CYP2C92, CYP2C93 and VKORC1-1639 variants on the susceptibility of upper gastrointestinal bleeding: A full case-control study.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques - 1 Jan 2023

Forgerini Marcela, Urbano Gustavo, De Nadai Tales Rubens, Batah Sabrina Setembre, Fabro Alexandre Todorovic, De Carvalho Mastroianni Patrícia

Abstract excerpt

Purpose: To investigate whether interindividual variability in the CYP2C9 (*2 and *3 alleles) and VKORC1 (rs9923231) genes is associated with increased risk of upper gastrointestinal bleeding (UGIB) in users of non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin (LDA). Methods: A full case-control study including 200 cases of patients diagnosed with UGIB and 706 controls was conducted in a...

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Identifiers

PMID: 36942299
DOI: 10.3389/jpps.2023.11136
PMCID: PMC9990631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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