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Article

Exploring the association between birthweight and breast cancer using summary statistics from a perspective of genetic correlation, mediation, and causality.

Journal of translational medicine - 14 May 2022

Zhang Meng, Qiao Jiahao, Zhang Shuo, Zeng Ping

Abstract excerpt

BACKGROUND: Previous studies demonstrated a positive relationship between birthweight and breast cancer; however, inconsistent, sometimes even controversial, observations also emerged, and the nature of such relationship remains unknown. METHODS: Using summary statistics of birthweight and breast cancer, we assessed the fetal/maternal-specific genetic correlation between them via LDSC and prioritized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35568861
DOI: 10.1186/s12967-022-03435-2
PMCID: PMC9107660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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