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DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the APOE4 Genotype in Rodents.

Nutrients - 19 Apr 2022

Pontifex Matthew G, Martinsen Anneloes, Saleh Rasha N M, Harden Glenn, Fox Chris, Muller Michael, Vauzour David, Minihane Anne-Marie

Abstract excerpt

Female APOE4 carriers have a greater predisposition to developing Alzheimer’s disease (AD) compared to their male counterparts, which may partly be attributed to menopause. We previously reported that a combination of menopause and APOE4 led to an exacerbation of cognitive and neurological deficits, which were associated with reduced brain DHA and DHA:AA ratio. Here, we explored whether DHA-enriched fish oil (FO)...

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PMID: 35565665
DOI: 10.3390/nu14091698
PMCID: PMC9103304

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