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Article

Comprehensive study of nine novel cases of TFEB ‐amplified renal cell carcinoma: an aggressive tumour with frequent PDL1 expression

14 May 2022

Abstract excerpt

AIMS: First described in 2014, renal cell carcinoma (RCC) with TFEB amplification (6p21) is a rare molecular subgroup whose diagnosis is challenging. The prognosis and therapeutic implications remain unclear. METHODS: We report here the clinical, histological, immunohistochemical, and genetic features of nine novel cases. The pathological and immunohistochemical features were centrally reviewed by expert...

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PMID: 35562857
DOI: 10.1111/his.14683

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