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Article

TFEB Expression Profiling in Renal Cell Carcinomas

30 Jul 2019

Abstract excerpt

TFEB is overexpressed in TFEB-rearranged renal cell carcinomas as well as in renal tumors with amplifications of TFEB at 6p21.1. As recent literature suggests that renal tumors with 6p21.1 amplification behave more aggressively than those with rearrangements of TFEB, we compared relative TFEB gene expression in these tumors. This study included 37 TFEB-altered tumors: 15 6p21.1-amplified and 22 TFEB-rearranged...

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PMID: 31600176
DOI: 10.1097/pas.0000000000001307

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