Article
Acute myeloid leukaemia: How to combine multiple tools.
International journal of laboratory hematology - 1 May 2018
Merino A, Boldú L, Ermens A
Abstract excerpt
The pathogenesis of acute myeloid leukaemias (AML) frequently requires at least 3 mutations in different cellular pathways. In many cases, mutations in proliferation/survival mechanisms and differentiation pathways are involved. Genetic aberrations explain the pathogenesis of AML, provide prognostic criteria and guide drug design for future therapy. Since the last update of the World Health Organization (WHO)...
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