Article
Higher basophil count decreases narcolepsy risk: a Mendelian randomization study.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Sept 2022
Li Ang, Li Hao, Xie Junyang, Xie Jianlei, Liao Wenjing, Song Lijuan, Zhang Xiaowen
Abstract excerpt
BACKGROUND: Blood cell properties effectively reflect immune status. Basophil and CD8+ CD27+ T cell levels are correlated with narcolepsy, but their causal association is unclear. This study aims to evaluate the causality between blood cell count and narcolepsy risk at the genetic level. METHODS: Two-sample Mendelian randomization (MR) analyses were performed on 35 published blood cell properties, using...
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