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Article

Variable Genomic Landscapes of Advanced Melanomas with Heavy Pigmentation.

The oncologist - 5 Aug 2022

Huang Richard S P, Tse Julie Y, Harries Lukas, Graf Ryon P, Lin Douglas I, Murugesan Karthikeyan, Hiemenz Matthew C, Parimi Vamsi, Janovitz Tyler, Decker Brennan, Severson Eric, Levy Mia A, Ramkissoon Shakti H, Elvin Julia A, Ross Jeffrey S, Williams Erik A

Abstract excerpt

BACKGROUND: In the current study, we examined the real-world prevalence of highly pigmented advanced melanomas (HPMel) and the clinicopathologic, genomic, and ICPI biomarker signatures of this class of tumors. MATERIALS AND METHODS: Our case archive of clinical melanoma samples for which the ordering physician requested testing for both PD-L1 immunohistochemistry (IHC) and comprehensive genomic profiling (CGP)...

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Source

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Identifiers

PMID: 35552752
DOI: 10.1093/oncolo/oyac090
PMCID: PMC9355815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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