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Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma

31 Mar 2012

Abstract excerpt

Chronic infections with the hepatitis B virus (HBV) and hepatitis C virus (HCV) are the major risks of hepatocellular carcinoma (HCC), and great efforts have been made towards the understanding of the different mechanisms that link the viral infection of hepatic lesions to HCC development. In this work, we developed a novel framework to identify distinct patterns of gene coexpression networks and...

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PMID: 22467683
DOI: 10.1093/jmcb/mjs011

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