Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel brown adipose tissue candidate genes predicted by the human gene connectome.

Scientific reports - 9 May 2022

Salazar-Tortosa Diego F, Enard David, Itan Yuval, Ruiz Jonatan R

Abstract excerpt

Brown adipose tissue (BAT) is a promising therapeutic target against obesity. Therefore, research on the genetic architecture of BAT could be key for the development of successful therapies against this complex phenotype. Hypothesis-driven candidate gene association studies are useful for studying genetic determinants of complex traits, but they are dependent upon the previous knowledge to select candidate genes....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue, Brown
Share to Connectome
Share to Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Thermogenesis

Share to Uncoupling Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 35534514
DOI: 10.1038/s41598-022-11317-2
PMCID: PMC9085833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel brown adipose tissue candidate genes predicted by the human gene connectome.PMID 35534514Read ↗

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesisSemantic proximity Read ↗

Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthySemantic proximity Read ↗

Thermogenic genes are blunted whereas brown adipose tissue identity is preserved in human obesitySemantic proximity Read ↗

Regulatory Modules of Human Thermogenic Adipocytes: Functional Genomics of Meta-Analyses Derived Marker-GenesSemantic proximity Read ↗

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.Semantic proximity Read ↗

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases.Semantic proximity Read ↗

Transcriptome-wide association study-derived genes as potential visceral adipose tissue-specific targets for type 2 diabetesSemantic proximity Read ↗

Insights into brown adipose tissue evolution and function from non-model organismsSemantic proximity Read ↗

WGCNA analysis of the subcutaneous fat transcriptome in a novel tree shrew modelSemantic proximity Read ↗

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite CellsSemantic proximity Read ↗

A UCP1-412A>C polymorphism is associated with abdominal fat area in Korean women.Semantic proximity Read ↗

The Mitochondrial Brown Adipose Tissue Maintenance Factor Nipsnap1 Interfaces Directly with the Beta-Oxidation Protein MachinerySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.