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Article

Biophysical Fitness Landscape of the SARS-CoV-2 Delta Variant Receptor Binding Domain.

Journal of molecular biology - 15 Jul 2022

Patrick Casey, Upadhyay Vaibhav, Lucas Alexandra, Mallela Krishna M G

Abstract excerpt

Among the five known SARS-CoV-2 variants of concern, Delta is the most virulent leading to severe symptoms and increased mortality among infected people. Our study seeks to examine how the biophysical parameters of the Delta variant correlate to the clinical observations. Receptor binding domain (RBD) is the first point of contact with the human host cells and is the immunodominant form of the spike protein....

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Share to Angiotensin-Converting Enzyme 2
Share to Antibodies, Monoclonal, Humanized

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 35533762
DOI: 10.1016/j.jmb.2022.167622
PMCID: PMC9076029

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