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Article

SARS-CoV-2 Variants, RBD Mutations, Binding Affinity, and Antibody Escape.

International journal of molecular sciences - 9 Nov 2021

Yang Lin, Li Jiacheng, Guo Shuai, Hou Chengyu, Liao Chenchen, Shi Liping, Ma Xiaoliang, Jiang Shenda, Zheng Bing, Fang Yi, Ye Lin, He Xiaodong

Abstract excerpt

Since 2020, the receptor-binding domain (RBD) of the spike protein of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been constantly mutating, producing most of the notable missense mutations in the context of "variants of concern", probably in response to the vaccine-driven alteration of immune profiles of the human population. The Delta variant, in particular, has become the most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34829998
DOI: 10.3390/ijms222212114
PMCID: PMC8619214

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