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Delta variant (B.1.617.2) of SARS-CoV-2: Mutations, impact, challenges and possible solutions.

Human vaccines & immunotherapeutics - 30 Nov 2022

Dhawan Manish, Sharma Abhilasha, Priyanka, Thakur Nanamika, Rajkhowa Tridib Kumar, Choudhary Om Prakash

Abstract excerpt

Since commencement of COVID-19 pandemic, several SARS-CoV-2 variants have emerged amid containment efforts via vaccination. The Delta variant (B.1.617.2), discovered in October 2020, was designated as a VOC by the WHO on May 11, 2021. The enhanced transmissibility of Delta variant has been associated with critical mutations such as D614G, L452R, P681R, and T478K in the S-protein. The increased affinity of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35507895
DOI: 10.1080/21645515.2022.2068883
PMCID: PMC9359381

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