Article
Biophysical and Biochemical Characterization of the Receptor Binding Domain of SARS-CoV-2 Variants.
The protein journal - 1 Oct 2022
Khatri Ritika, Parray Hilal Ahmad, Siddiqui Gazala, Chiranjivi Adarsh Kumar, Raj Sneha, Kaul Rachel, Maithil Vikas, Samal Sweety, Ahmed Shubbir
Abstract excerpt
The newly emerging SARS-CoV-2 variants are potential threat and posing new challenges for medical intervention due to high transmissibility and escaping neutralizing antibody (NAb) responses. Many of these variants have mutations in the receptor binding domain (RBD) of SARS-CoV-2 spike protein that interacts with the host cell receptor. Rapid mutation in the RBD through natural selection to improve affinity for...
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