Article

Altered interaction between RBD and ACE2 receptor contributes towards the increased transmissibility of SARS CoV-2 delta, kappa, beta, and gamma strains with RBD double mutations

2021-08-31

Abstract excerpt

<h4>ABSTRACT</h4> The COVID-19 pandemics by SARS-CoV-2 causes catastrophic damage for global human health. The initial step of SARS-CoV-2 infection is the binding of the receptor-binding domain (RBD) in its spike protein to ACE2 receptor in host cell membrane. The evolving of SARS-CoV-2 constantly generates new mutations across its genome including RBD. Besides the well-known single mutation in RBD, the recent ne...

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Literature Corpus work: aa8083f2-1e9d-51fa-9ea7-5a84cf191ea4
DOI: 10.1101/2021.08.30.458303

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