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Article

Primary Human Nasal Epithelial Cells: Biobanking in the Context of Precision Medicine.

Journal of visualized experiments : JoVE - 22 Apr 2022

Kelly Mairead, Dreano Elise, Hatton Aurelie, Lepissier Agathe, Golec Anita, Sermet-Gaudelus Isabelle, Pranke Iwona

Abstract excerpt

Human nasal epithelial (HNE) cells are easy to collect by simple, non-invasive nasal brushing. Patient-derived primary HNE cells can be amplified and differentiated into a pseudo-stratified epithelium in air-liquid interface conditions to quantify cyclic AMP-mediated Chloride (Cl-) transport as an index of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) function. If critical steps such as quality of...

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PMID: 35532277
DOI: 10.3791/63409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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