Article
Brain somatic mutations as RNA therapeutic targets in neurological disorders.
Annals of the New York Academy of Sciences - 1 Aug 2022
Lee Sungyul, Lee Jeong Ho
Abstract excerpt
Research into the genetic etiology of a neurological disorder can provide directions for genetic diagnosis and targeted therapy. In the past, germline mutations, which are transmitted from parents or newly arise from parental germ cells, were considered as major genetic causes of neurological disorders. However, recent evidence has shown that somatic mutations in the brain, which can arise from neural stem cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
