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Article

Somatic mutations in disorders with disrupted brain connectivity.

Experimental & molecular medicine - 10 Jun 2016

Lee Jeong Ho

Abstract excerpt

Mutations occur during cell division in all somatic lineages. Because neurogenesis persists throughout human life, somatic mutations in the brain arise during development and accumulate with the aging process. The human brain consists of 100 billion neurons that form an extraordinarily intricate network of connections to achieve higher level cognitive functions. Due to this network architecture, perturbed...

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Identifiers

PMID: 27282107
DOI: 10.1038/emm.2016.53
PMCID: PMC4929695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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