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Article

Burden of rare coding variants reveals genetic heterogeneity between obese and non-obese asthma patients in the African American population.

Respiratory research - 6 May 2022

Liu Yichuan, Qu Hui-Qi, Qu Jingchun, Chang Xiao, Mentch Frank D, Nguyen Kenny, Tian Lifeng, Glessner Joseph, Sleiman Patrick M A, Hakonarson Hakon

Abstract excerpt

BACKGROUND: Asthma is a complex condition largely attributed to the interactions among genes and environments as a heterogeneous phenotype. Obesity is significantly associated with asthma development, and genetic studies on obese vs. non-obese asthma are warranted. METHODS: To investigate asthma in the minority African American (AA) population with or without obesity, we performed a whole genome sequencing (WGS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 35524249
DOI: 10.1186/s12931-022-02039-0
PMCID: PMC9078008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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