Article
Obesity-related biomarkers underlie a shared genetic architecture between childhood body mass index and childhood asthma.
Communications biology - 17 Oct 2022
Han Xikun, Zhu Zhaozhong, Xiao Qian, Li Jun, Hong Xiumei, Wang Xiaobin, Hasegawa Kohei, Camargo Carlos A, Liang Liming
Abstract excerpt
Obesity and asthma are both common diseases with high population burden worldwide. Recent genetic association studies have shown that obesity is associated with asthma in adults. The relationship between childhood obesity and childhood asthma, and the underlying mechanisms linking obesity to asthma remain to be clarified. In the present study, leveraging large-scale genetic data from UK biobank and several other...
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