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Article

Associations between human leukocyte antigen class I variants and the Mycobacterium tuberculosis subtypes causing disease.

The Journal of infectious diseases - 15 Jan 2014

Salie Muneeb, van der Merwe Lize, Möller Marlo, Daya Michelle, van der Spuy Gian D, van Helden Paul D, Martin Maureen P, Gao Xiao-Jiang, Warren Robin M, Carrington Mary, Hoal Eileen G

Abstract excerpt

BACKGROUND: The development of active tuberculosis disease has been shown to be multifactorial. Interactions between host and bacterial genotype may influence disease outcome, with some studies indicating the adaptation of M. tuberculosis strains to specific human populations. Here we investigate the role of the human leukocyte antigen (HLA) class I genes in this biological process. METHODS: Three hundred...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23945374
DOI: 10.1093/infdis/jit443
PMCID: PMC3873786

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