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Article

Distribution of HLA-DRB1 alleles in BRICS countries with a high tuberculosis burden: a systematic review and meta-analysis.

Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2021

Sarno Alice, Daltro Cleidiane Borges, Mendes Carlos Mauricio Cardeal, Barbosa Theolis

Abstract excerpt

INTRODUCTION: Tuberculosis (TB) is the leading cause of death worldwide caused by a single infectious disease agent. Brazil, Russia, India, China, and South Africa (BRICS) account for more than half of the world's TB cases. Bacillus Calmette-Guérin (BCG) remains the only vaccine available despite its variable efficacy. Promising antigen-based vaccines have been proposed as prophylactic and/or immunotherapeutic...

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Identifiers

PMID: 34320128
DOI: 10.1590/0037-8682-0017-2021
PMCID: PMC8313104

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