Non-coding genetic variation in regulatory elements determines thrombosis and hemostasis phenotypes.

Abstract excerpt

Since the early inception of genome-wide association studies (GWAS), it became clear that, in all diseases or traits studied, most genetic variants are likely to exert their effect on gene expression mainly by altering the function of regulatory elements. At the same time, the regulation of the gene expression field broadened its boundaries, from the univocal relationship between regulatory elements and genes to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Enhancer Elements, Genetic
• Share to Genetic Variation
• Share to Genome-Wide Association Study