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Leveraging artificial intelligence to predict ERG gene fusion status in prostate cancer

5 May 2022

Abstract excerpt

BACKGROUND: TMPRSS2-ERG gene rearrangement, the most common E26 transformation specific (ETS) gene fusion within prostate cancer, is known to contribute to the pathogenesis of this disease and carries diagnostic annotations for prostate cancer patients clinically. The ERG rearrangement status in prostatic adenocarcinoma currently cannot be reliably identified from histologic features on H&E-stained slides alone...

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PMID: 35513774
DOI: 10.1186/s12885-022-09559-4

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