Association Between Bitter Taste Receptor Phenotype and Clinical Outcomes Among Patients With COVID-19.

doi:10.1001/jamanetworkopen.2021.11410

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Article

Association Between Bitter Taste Receptor Phenotype and Clinical Outcomes Among Patients With COVID-19.

JAMA network open - 3 May 2021

Barham Henry P, Taha Mohamed A, Broyles Stephanie T, Stevenson Megan M, Zito Brittany A, Hall Christian A

Abstract excerpt

Importance: Bitter taste receptors (T2Rs) have been implicated in sinonasal innate immunity, and genetic variation conferred by allelic variants in T2R genes is associated with variation in upper respiratory tract pathogen susceptibility, symptoms, and outcomes. Bitter taste receptor phenotype appears to be associated with the clinical course and symptom duration of SARS-CoV-2 infection. Objective: To evaluate...

Topics

Adult
Alleles
COVID-19
Female
Genetic Variation
Hospitalization
Humans
Immunity, Innate
Male
Middle Aged
Odds Ratio
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prospective Studies

Protective Factors

Receptors, G-Protein-Coupled

SARS-CoV-2

Severity of Illness Index

Taste

Source

Open in PubMed Open full text

Identifiers

PMID: 34032852
DOI: 10.1001/jamanetworkopen.2021.11410
PMCID: PMC8150696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34032852-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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