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Article

No optical coherence tomography changes in premanifest Huntington's disease mutation carriers far from disease onset.

Brain and behavior - 1 Jun 2022

Schmid Rahel Dominique, Remlinger Jana, Abegg Mathias, Hoepner Robert, Hoffmann Rainer, Lukas Carsten, Saft Carsten, Salmen Anke

Abstract excerpt

BACKGROUND: Spectral-domain optical coherence tomography (OCT) may detect retinal changes as a biomarker in neurodegenerative diseases like manifest Huntington's disease (HD). We investigate macular retinal layer thicknesses in a premanifest HD (pre-HD) cohort and healthy controls (HC). METHODS: Pre-HD mutation carriers underwent standardized ratings and a preset macular OCT scan. Thickness values were determined...

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Identifiers

PMID: 35511084
DOI: 10.1002/brb3.2592
PMCID: PMC9226796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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