Article
Donor with HLA-C2 is associated with acute rejection following liver transplantation in Southern Chinese.
HLA - 1 Aug 2022
Chen Rui, Yi Huimin, Zhen Jianxin, Fan Mingming, Xiao Lulu, Yu Qiong, Yang Zhichao, Ning Li, Deng Zhihui, Chen Guihua
Abstract excerpt
Apart from presenting peptides to T cells, class I HLA molecules serve as ligands for killer cell immunoglobulin-like receptor (KIRs) and regulate the response of natural killer (NK) cells. The role played by HLA and KIR in the acute rejection (AR) following liver transplantation has been controversial. In this retrospective study, we assessed the influence of class I HLA alleles, HLA matching between...
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