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Article

KLF4 regulates TERT expression in alveolar epithelial cells in pulmonary fibrosis

4 May 2022

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) was considered as a telomere-mediated disease. TERT and TERC correlated with telomere length. Although telomerase gene mutations were associated with IPF, majority patients did not carry mutations. The mechanism by which telomerase expression was regulated in IPF are still unclear. In this study, we aimed to delineate the mechanisms that how TERT protein expression were...

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PMID: 35508454
DOI: 10.1038/s41419-022-04886-7

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