Article
Modeling Treatment Response for Lamin A/C Related Dilated Cardiomyopathy in Human Induced Pluripotent Stem Cells.
Journal of the American Heart Association - 28 Jul 2017
Lee Yee-Ki, Lau Yee-Man, Cai Zhu-Jun, Lai Wing-Hon, Wong Lai-Yung, Tse Hung-Fat, Ng Kwong-Man, Siu Chung-Wah
Abstract excerpt
BACKGROUND: Precision medicine is an emerging approach to disease treatment and prevention that takes into account individual variability in the environment, lifestyle, and genetic makeup of patients. Patient-specific human induced pluripotent stem cells hold promise to transform precision medicine into real-life clinical practice. Lamin A/C (LMNA)-related cardiomyopathy is the most common inherited...
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