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CDC20 in and out of mitosis: a prognostic factor and therapeutic target in hematological malignancies

30 Apr 2022

Abstract excerpt

Abstract Cell division cycle 20 homologue (CDC20) is a well-known regulator of cell cycle, as it controls the correct segregation of chromosomes during mitosis. Many studies have focused on the biological role of CDC20 in cancer development, as alterations of its functionality have been linked to genomic instability and evidence demonstrated that high CDC20 expression levels are associated with poor overall...

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PMID: 35490245
DOI: 10.1186/s13046-022-02363-9

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