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Cell division cycle 20 promotes cell proliferation and invasion and inhibits apoptosis in osteosarcoma cells

5 Oct 2017

Abstract excerpt

Cdc20 (cell division cycle 20 homologue) has been reported to exhibit an oncogenic role in human tumorigenesis. However, the function of Cdc20 in osteosarcoma (OS) has not been investigated. In the current study, we aim to explore the role of Cdc20 in human OS cells. Multiple approaches were used to measure cell growth, apoptosis, cell cycle, migration and invasion in OS cells after depletion of Cdc20 or...

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PMID: 28980876
DOI: 10.1080/15384101.2017.1387700

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