Article
Thada Is Dispensable for Female Fertility in Mice.
Frontiers in endocrinology - 1 Jan 2022
Han Shan, Zhang Yuqing, Zheng Yukun, Liu Congcong, Jiang Yonghui, Zhao Shigang, Zhao Han
Abstract excerpt
Genome-wide association studies (GWAS) have identified THADA as one of the susceptibility genes for polycystic ovary syndrome (PCOS). Single nucleotide polymorphisms (SNPs) in the THADA gene showed significant over-transmission in PCOS and strong correlations with testosterone level. However, there was insufficient evidence to verify the effect of THADA in vivo on female reproductive system. In this study, we...
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