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THADA Regulates the Organismal Balance between Energy Storage and Heat Production.

Developmental cell - 10 Apr 2017

Moraru Alexandra, Cakan-Akdogan Gulcin, Strassburger Katrin, Males Matilda, Mueller Sandra, Jabs Markus, Muelleder Michael, Frejno Martin, Braeckman Bart P, Ralser Markus, Teleman Aurelio A

Abstract excerpt

Human susceptibility to obesity is mainly genetic, yet the underlying evolutionary drivers causing variation from person to person are not clear. One theory rationalizes that populations that have adapted to warmer climates have reduced their metabolic rates, thereby increasing their propensity to store energy. We uncover here the function of a gene that supports this theory. THADA is one of the genes most...

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Identifiers

PMID: 28399403
DOI: 10.1016/j.devcel.2017.03.016
PMCID: PMC5392496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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