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Article

Mutational meltdown of putative microbial altruists in Streptomyces coelicolor colonies.

Nature communications - 27 Apr 2022

Zhang Zheren, Shitut Shraddha, Claushuis Bart, Claessen Dennis, Rozen Daniel E

Abstract excerpt

In colonies of the filamentous multicellular bacterium Streptomyces coelicolor, a subpopulation of cells arises that hyperproduces metabolically costly antibiotics, resulting in a division of labor that increases colony fitness. Because these cells contain large genomic deletions that cause massive reductions to individual fitness, their behavior is similar to altruistic worker castes in social insects or somatic...

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Identifiers

PMID: 35477578
DOI: 10.1038/s41467-022-29924-y
PMCID: PMC9046218

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