Article
The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis.
Genetics - 1 Oct 2007
Maughan Heather, Masel Joanna, Birky C William, Nicholson Wayne L
Abstract excerpt
Phenotypic loss is an important evolutionary force in nature but the mechanism(s) responsible for loss remains unclear. We used both simulation and multiple-regression approaches to analyze data on the loss of sporulation, a complex bacterial developmental process, during experimental evolution of Bacillus subtilis. Neutral processes of mutational degradation alone were sufficient to explain loss-of-sporulation...
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